Interestingly, there was a highly significant overlap ( P -value 1.7e −12 ) between this study and the Runx1 negatively correlated genes reported here, which included Sox17, ectopic expression of which was recently shown to induce apoptosis in early ES cell-derived blood progenitors ( Serrano et al., 2010 ).
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The transcriptional programme controlled by Runx1 during early embryonic blood development.
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