Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53.

Interestingly, some of the other highly significant hits (PRP19, CDC5L, PLRG1, BCAS2) are core members of the PRP19 complex [30] – [32] which has previously been shown to be required for pre-mRNA splicing in yeast [15] – [16] and for DNA repair in both yeast and human cells [33] – [37] .

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