Quetiapine and Buspirone Both Elevate Cortical Levels of Noradrenaline and Dopamine In vivo, but Do Not have Synergistic Effects.

Administration of quetiapine resulted in a somewhat higher elevation of dopamine levels which was also highly significant compared to saline controls (Dunnett’s Multiple Comparison Test 56.2, p < 0.001), an effect that also persisted until the end of the experiment where dopamine levels were 180% of baseline (Figure 3 ).

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