NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma.

Oncotarget · 2012 · PMC3443255 · PMID 22869051

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highly significantno p-value reported

The over-expression of miR-145 affects the aggressive and invasive features of GB-NS, as confirmed by a greater differentiation of the tumor phenotype and a highly significant decrease in NEDD9, supporting the concept that miR-145 plays an important role in glioblastoma invasiveness by regulating NEDD9.

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