Centrality-based pathway enrichment: a systematic approach for finding significant pathways dominated by key genes.

BMC Syst Biol · 2012 · PMC3443660 · PMID 22672776

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closest p · 0.2× alpha

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boldest claim

The sentences

highly significantp -value < 0.01actually significant

As illustrated in Figure 3 , when selecting high-degree differential nodes, provided that the number of differential nodes is 5 or greater, the pathway is highly significant ( p -value < 0.01).

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