Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration.

Arthritis Res Ther · 2012 · PMC3446417 · PMID 22394620

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an increasing trendno p-value reported

TIMP-1 exhibited no significant change but did show an increasing trend toward up-regulation.

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