A flow cytometry-based assay for quantifying non-plaque forming strains of yellow fever virus.

There was a strong and highly significant correlation between virus titers measured by TC-LDA and qRT-PCR (R 2 = 0.89, P <0.0001; Figure 5 ) and the slope of the line indicates that there is approximately a 1∶1 relationship between the number of infectious virus particles and virus genome equivalents identified in these serum samples.

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