Appropriate patient instructions can reduce prostate motion.

Radiat Oncol · 2012 · PMC3447725 · PMID 22852559

Europe PMC DOI

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might be significantno p-value reported

Marker based corrections have shown in numerous studies (see discussion), that the uncertainties caused by the prostate movement might be significant requiring safety margins > 1 cm.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.