Diabetes-impaired wound healing is improved by matrix therapy with heparan sulfate glycosaminoglycan mimetic OTR4120 in rats.

Diabetes · 2012 · PMC3447910 · PMID 22721969

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0.0800

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0.0800

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almost significantlyP = 0.08so close (0.05 < p ≤ 0.1)

After STZ injection, from 78 days onwards, the average weight restoration was, almost significantly, higher in the OTR4120-treated rats than in control rats (87 vs. 80% on day 78, P = 0.08; 90 vs. 81% on day 85, P = 0.02; 91 vs. 83% on day 99, P = 0.08; and 87 vs. 77% on day 134, P = 0.06) ( Fig. 1 ).

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