The association was evaluated in two stages and both the SNPs resulted associated with hypertension with marginally significant p-value.
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The Renalase Asp37Glu polymorphism is not associated with hypertension and cardiovascular events in an urban-based prospective cohort: the Malmö Diet and cancer study.
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The sentences
When further adjustment for traditional cardiovascular risk factors (including smoking habit, previous cardiovascular events, hypertension, diabetes mellitus, total cholesterol) was included in the models the results did not change substantially but a borderline significant difference was noticed for incident coronary events in RNLS rs2296545 GG-homozygotes as compared to C-carriers and for incident atrial fibrillation/flutter in RNLS rs2576178 G-carriers with respect to AA-homozygotes (Table 4 ).