Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis.

Nat Genet · 2012 · PMC3459817 · PMID 22961000

Europe PMC DOI

hedged sentence

0.0680

closest p · 1.4× alpha

0.0680

boldest claim

The sentences

just failed to reach significanceP = 0.068so close (0.05 < p ≤ 0.1)

Considering only loci where the most associated SNP achieved genome-wide significance ( N =21, excluding the HLA locus, SNPs outside Immunochip fine-mapping regions and SNPs with MAF<5%), Gm12878 had the highest enrichment score compared with the other cell lines, though the difference in enrichment just failed to reach significance (P = 0.068 Online Methods) ( Figure 2 ).

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