highly significantp = 0.008
Only 3 out of the 46 outcome measures in common in the two studies showed significant differences and only one was highly significant: In PPMS there was greater progression in the EDSS sensory system by either definition 1 (p = 0.008) or definition 2 (p = 0.04) and in SPMS there was greater progression in the 9HP but only using definition 2 (p = 0.04, Table 3 ).