highly significantp<0.001
The reduction in the depression score from the first to the second visit (Wilcoxon signed test: V = 171.00, p<0.001) and differences between patients and controls were highly significant (Mann-Witney test; patients V1 and controls: U = 972.00, p<0.001; patients V2 and controls: U = 839.00, p<0.001).