Single mutations in the transmembrane envelope protein abrogate the immunosuppressive property of HIV-1.

Retrovirology · 2012 · PMC3464125 · PMID 22889273

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might be significantno p-value reported

Thus, taking this point into consideration, the gp41 induced immunosuppression might be significant when the load of infectious virus is much lower than 1 × 10 6 /ml.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.