Comprehensive analysis of common serum liver enzymes as prospective predictors of hepatocellular carcinoma in HBV patients.

PLoS One · 2012 · PMC3480412 · PMID 23112834

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an increasing trendno p-value reported

An increasing trend of cumulative HCC incidences over the follow-up period was observed for all four enzymes.

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highly significantno p-value reported

In the univariate analysis, a highly significant dose response was observed ( P trend<0.001 for all analyses, Table S4 ).

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borderline significantno p-value reported

Males and ever smokers had a borderline significant increase in HCC risk ( P value, 0.091 and 0.066, respectively).

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