Bisphosphonates and risk of upper gastrointestinal cancer--a case control study using the General Practice Research Database (GPRD).

PLoS One · 2012 · PMC3480418 · PMID 23112825

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a decreasing trendno p-value reported

Overall they found bisphosphonates had been prescribed to 7.8% of the cases versus 3.6% of the controls, however they then break the analysis down by frequency of use of bisphosphonates and find a decreasing trend of ORs from rare to regular users of 3.86 to 2.68 and also with time observed and conclude that there is no effect.

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