Multicentric reticulohistiocytosis.

Indian Dermatol Online J · 2011 · PMC3481828 · PMID 23130232

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may be significantno p-value reported

The proliferation of histiocytes can be a paraneoplastic response and there may be significant morbidity and mortality because of joint involvement and malignancy.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.