Highly significant linkage disequilibrium was shown among exons 12 C1236T, 21 G2677T and 26 C3435T, which could account for most of the haplotypes (combinations of SNPs) seen in ABCB1 [ 13 - 15 ].
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Blood-brain barrier P-glycoprotein function in healthy subjects and Alzheimer's disease patients: effect of polymorphisms in the ABCB1 gene.
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