Folate Intake, MTHFR Polymorphisms, and the Risk of Colorectal Cancer: A Systematic Review and Meta-Analysis.

J Cancer Epidemiol · 2012 · PMC3483802 · PMID 23125859

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may not be significantno p-value reported

Whereas, for the MTHFR 677 TT genotype, the Begg and Mazumdar test returned a P value = 0.33, Egger's a P value = 0.38, and Trim and Fill found that additional 4 studies would be necessary to form a symmetrical funnel plot, suggesting that publication bias may not be significant concern. 3.1.4.

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