Cytokines in the systemic inflammatory response syndrome: a review.

HSR Proc Intensive Care Cardiovasc Anesth · 2010 · PMC3484588 · PMID 23441054

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The following substances may be significant to the molecular basis of SIRS: Haemoxygenase-1 (HO-1) - implicated in the defensive response to oxidative stress; it has been found to attenuate TNFα mRNA synthesis and plasma TNFá levels, reduce lung injury and improves organ perfusion [ 33 ].

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