Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases.

PLoS One · 2012 · PMC3485301 · PMID 23118876

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0520

boldest claim

The sentences

highly significantp = 0.001actually significant

The microarray finding could be confirmed, and a statistically highly significant down regulation of PRKCDBP was found among the BCBM samples compared to the primary BC (p = 0.001) ( Figure 2 ).

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borderline significantp = 0.052so close (0.05 < p ≤ 0.1)

However, AI at the most telomeric marker D11S2071 showed a borderline significant association with earlier relapse compared to patients not showing and AI around this locus (p = 0.052)( Figure S1 ).

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borderline significanceno p-value reported

In the primary BC samples the most telomeric marker D11S2071 was associated with worse prognosis (borderline significance) and triple negative (TNBC) tumor type.

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