Disruption of CHTF18 causes defective meiotic recombination in male mice.

PLoS Genet · 2012 · PMC3486840 · PMID 23133398

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highly significantno p-value reported

Univalent chromosomes (as many as six) were present in 20% (35 cells counted) of Chtf18 −/− metaphase I spermatocytes ( Figure 7H ), a number that is highly significant in light of the fact that such chromosomes were not observed in spermatocytes of wild-type males (50 cells counted).

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