Adaptive evolution and the birth of CTCF binding sites in the Drosophila genome.

PLoS Biol · 2012 · PMC3491045 · PMID 23139640

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highly significantp <1e-6actually significant

The association of newly evolved essential genes with newly evolved CTCF binding sites is highly significant compared to old essential genes with conserved CTCF binding sites (Kolmogorov-Smirnov test, p <1e-6; Figure S19 ).

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