Abnormal anatomical connectivity between the amygdala and orbitofrontal cortex in conduct disorder.

PLoS One · 2012 · PMC3492256 · PMID 23144970

Europe PMC DOI

hedged sentences

0.0005

closest p · 0.0× alpha

0.0700

boldest claim

The sentences

highly significantP<0.0005actually significant

Further ANCOVAs exploring the effects of group and hemisphere for each tract showed a highly significant effect of group for the UF, F(1,23) = 20.03, P<0.0005, and no corresponding effect for the IFOF, F(1,23) = 0.16, P>0.6.

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of borderline significanceP = 0.06so close (0.05 < p ≤ 0.1)

Hence, the group by tract interaction remained unchanged, F(1,23) = 8.67, P<0.01, while the effect of group for the UF remained significant, F(1,22) = 5.11, P = 0.03, although it was of borderline significance (P = 0.06) when correcting for multiple comparisons using the Bonferroni procedure.

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borderline significantP = 0.07so close (0.05 < p ≤ 0.1)

When analysing which of the axial (λ1 eigenvalues) or radial diffusivity (λ2, λ3 eigenvalues) measures was contributing to the main effect of the group for the FA in the UF, we found borderline significant effects for both variables (P = 0.07 for λ1 and P = 0.09 for λ3) ( Tables S1 , S2 , S3 , S4 , S5 , S6 ).

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