mRNA-Seq of single prostate cancer circulating tumor cells reveals recapitulation of gene expression and pathways found in prostate cancer.

Numbers of completely purified CTCs enumerated by MagSweeper isolation and CellSearch were compared and found to be reasonably similar, with a mild trend observed toward better CTC capture using the MagSweeper in samples with low CTC numbers ( Figure 1E ).

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Repeating these analyses with only genes identified in P2 verses normal prostate tissue produced very similar results with highly significant p-values.

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