Imbalances between matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) in maternal serum during preterm labor.

PLoS One · 2012 · PMC3493509 · PMID 23145060

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Multiple regression analyses showed a strong association with preterm status, as MMP-9:TIMP-1 and MMP-9:TIMP-2 ratios were markedly significant higher for the key covariate preterm, while for the key covariate labor only the MMP-9:TIMP-2 ratio was significantly higher.

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