In surgically treated patients, the models with tCK18 and cCK18 as continuous variables (log transformed to base 2) were borderline significant, but in general, the prognostic associations of tCK18 and cCK18 were attenuated after adjustment included stage ( Table 2 ).
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Multi-level evidence that circulating CK18 is a biomarker of tumour burden in colorectal cancer.
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