Estimation and comparison of osteopontin levels in plasma in subjects with healthy periodontium and generalized chronic periodontitis and its assessment after scaling and root planing.

The results of the study are consistent with outcomes of recent investigations which reported which reported an elevation of OPN in periodontitis patients.[ 6 , 11 , 12 ] The results of our study are similar to a study by Sharma and Pradeep.[ 6 ] They found a highly significant elevation of OPN plasma in subjects with chronic periodontitis group as compared with the healthy group.

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