Barely Significant
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PGE2 induces interleukin-8 derepression in human astrocytoma through coordinated DNA demethylation and histone hyperacetylation.

Epigenetics · 2012 · PMC3499332 · PMID 23051921

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highly significantno p-value reported
Dissociation and or masking of HDAC2 and 3 was highly significant 2 h after PGE2 treatment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.