highly significantp<6.59×10 −6
In addition, tests of specific models were also highly significant; the genotypic test for rs634990 gave p<6.59×10 −6 , the additive model gave p<1.45×10 −6 , the dominant model showed increased risk with a p<1.91×10 −5 (OR=2.12, 95% CI=1.50–3.01), and a comparison of the homozygous GG and AA genotypes gave p<3.09×10 −6 (OR=3.12, 95% CI=1.91–5.07).