A common trinucleotide repeat expansion within the transcription factor 4 (TCF4, E2-2) gene predicts Fuchs corneal dystrophy.

PLoS One · 2012 · PMC3504061 · PMID 23185296

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highly significantno p-value reported

Baratz and colleagues described results of a genome-wide association study (GWAS) that revealed a highly significant association between single nucleotide polymorphisms (SNPs), most notably rs613872, in the transcription factor 4 ( TCF4 ) gene and typical, late onset FECD.

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