highly significantP <0.001
A p -value of <0.05 (*) was considered as significant, p -value of <0.01(**) was highly significant and P <0.001 (***) was very highly significant.
A p -value of <0.05 (*) was considered as significant, p -value of <0.01(**) was highly significant and P <0.001 (***) was very highly significant.