Nuclear Smad7 Overexpressed in Mesenchymal Cells Acts as a Transcriptional Corepressor by Interacting with HDAC-1 and E2F to Regulate Cell Cycle.

Biol Open · 2012 · PMC3507285 · PMID 23213415

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Despite the unclear role of HDAC-3 on Smad7 activity, their interaction in vivo might be significant for adipogenesis because both Smad7 and a combination of HDAC-3 and pRb can influence adipocyte differentiation ( Choy et al., 2000 ; Fajas et al., 2002 ).

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