In individuals without type 2 diabetes, there was a nonsignificant trend toward higher LAV*LVMI and E/e′ ratio with higher BNP.
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Prospective associations of B-type natriuretic peptide with markers of left ventricular function in individuals with and without type 2 diabetes: an 8-year follow-up of the Hoorn Study.
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The sentences
There was an overall trend toward more deterioration of LV systolic and diastolic function in individuals without type 2 diabetes with higher BNP levels, but this was only statistically significant for LA volume index and LVMI/LVEDVI.