SLiMPrints: conservation-based discovery of functional motif fingerprints in intrinsically disordered protein regions.

Using data from the eIF2A alignment ( Figure 7 A) and LIG_eIF4E_1, we performed a SLiMSearch ( 23 ) analysis of YxPPx[ILMVA][KR] instances in the human proteome: all highly significant hits ( Sig motif <0.001) occur in messenger RNA (mRNA) translation-related proteins ( Table 2 ), with the exception of carnitine deficiency-associated gene expressed in ventricle 3 (CDV3), which has no known function.

also in 132,142 other papers