Immuno-isolation of pancreatic islet allografts using pegylated nanotherapy leads to long-term normoglycemia in full MHC mismatch recipient mice.

4 ) – a highly significant point and, even though the in vitro model has its limitations in fully mimicking the cell destructive process after transplantation, the data clearly demonstrate that pegylated, nanoparticle decorated islets have superior survival advantages over naked islets.

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