Correlation of Baseline Characteristics with Intrahepatic Lipid Biochemistry Although many patients had liver biochemistry (ALT, AST and GGT) within the normal reference range, there were highly significant correlations between IHCL and serum levels of ALT (ρ = 0.47), AST (ρ = 0.49), and GGT (ρ = 0.50) (all p<0.05).
There was a significant correlation between relative IHL reduction and relative reduction in HbA1c percentage (ρ = 0.49,p = 0.01); the correlation between absolute changes fell just short of statistical significance (ρ = 0.38,p = 0.06), not surprisingly given the wide range of starting values of IHL, and the strong relationship between the starting IHL and the absolute reduction in IHL (see below).