Histone demethylase Jumonji D3 (JMJD3) as a tumor suppressor by regulating p53 protein nuclear stabilization.

PLoS One · 2012 · PMC3517524 · PMID 23236496

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highly significantno p-value reported

For example, primary GBM 827 (GBM 827-P) demonstrates highly significant levels of methylation at the JMJD3 regulatory element relative to non-tumor brain tissue and other tumor samples ( Figure 6A ; red arrow).

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