High-resolution mapping of linear antibody epitopes using ultrahigh-density peptide microarrays.

Mol Cell Proteomics · 2012 · PMC3518105 · PMID 22984286

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highly significantp < 0.00001actually significant

4 ), resulted in PSSMs showing a highly significant pattern of selective positions indicative of the presence of antibody epitopes ( p < 0.00001, ANOVA); 95% of these epitopes appeared fully contained within the 15-mer stretch selected for the fine specificity analysis, whereas the remaining 5% extended to the N- or C-terminus of the selected 15-mer stretch and could potentially extend even further.

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