Barely Significant
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A spruce gene map infers ancient plant genome reshuffling and subsequent slow evolution in the gymnosperm lineage leading to extant conifers.

BMC Biol · 2012 · PMC3519789 · PMID 23102090

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The sentences

highly significantP < 2.2e -16actually significant
This difference was highly significant ( χ 2 = 482.2; P < 2.2e -16 ), indicating that ancient gene pairs have been highly dispersed.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.