Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established.

PLoS One · 2012 · PMC3521014 · PMID 23251341

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highly significantno p-value reported

In contrast, infected animals treated with inactivated 244 DI virus showed a pronounced and highly significant weight loss on day 3, falling to below their initial mean group weight.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.