highly significantP <0.0001
While there was a highly significant main effect of dose (F[2,153] = 30.2; P <0.0001; Figure 2F ), there was no main effect of genotype (F[2,153] = 0.045; P = 0.96), nor was there an interaction between genotype and dose (F[2,153] = 0.085; P = 0.99).