Biomarkers on melanoma patient T cells associated with ipilimumab treatment.

J Transl Med · 2012 · PMC3527361 · PMID 22788688

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highly significantno p-value reported

Ipilimumab appeared to release the arrested cell cycle in CD4 + and CD8 + T cells as evidenced by highly significant and consistent up-regulation of CDC2 (Table 2 a and 2 b), and other cell cycle related genes (data not shown).

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