An Early Morning Sputum Sample Is Necessary for the Diagnosis of Pulmonary Tuberculosis, Even with More Sensitive Techniques: A Prospective Cohort Study among Adolescent TB-Suspects in Uganda.

Tuberc Res Treat · 2012 · PMC3529437 · PMID 23304491

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may not be significantno p-value reported

We observed less contamination with spot samples (which were supervised at collection sites) when compared with the EM samples (which were not unsupervised at collection sites); however, this may not be significant since we did not provide patients with water or other materials to minimize normal flora prior to expectoration.

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