ENU-induced phenovariance in mice: inferences from 587 mutations.

Interestingly T→C mutations show even stronger strand asymmetry among phenotypic mutations, and are over-represented to a highly significant degree in the sense strand (P = 0.00071), but are not over-represented among incidental mutations.

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A selective trend toward significance among phenotypic mutations is also observed for A→C/T→G (sense/antisense) among phenotypic mutations, and for G→A/C→T (sense/antisense) among both phenotypic and incidental mutations (Table 5 ).

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