Atomistic study of lipid membranes containing chloroform: looking for a lipid-mediated mechanism of anesthesia.

PLoS One · 2013 · PMC3534722 · PMID 23300982

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First, membrane structural modifications are evident at saturation conditions, but almost insignificant at clinically relevant concentrations: membranes with 12 chlf molecules show negligible variations in area per molecule, thickness and lipid ordering.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.