8 ), in which N was estimated using ionic mean–variance analysis and Q max was obtained by integrating gating currents, slightly underestimated the true value of Δ q T = 2.62 e o by −2.4%, a difference that is close to being statistically significant (P = 0.055).
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A linkage analysis toolkit for studying allosteric networks in ion channels.
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0.0550
0.0550