Phosphodiesterase inhibition mediates matrix metalloproteinase activity and the level of collagen degradation fragments in a liver fibrosis ex vivo rat model.

BMC Res Notes · 2012 · PMC3541216 · PMID 23249435

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highly significantno p-value reported

We found a highly significant, and more than 100% fold up regulation of the neo-epitope in fibrotic liver tissue compared to the vehicle tissue in the ex vivo liver tissue cultures.

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