An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones.

However, when comparing the numbers of marked cell achieved at days 6 or 50 between the two viruses the differences are highly significant ( P <0.0009) with higher frequency of marking achieved by the ICP0Cre recombinant at both acute and latent time points.

also in 132,142 other papers