p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome.

Hum Mol Genet · 2013 · PMC3542863 · PMID 23108156

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highly significantno p-value reported

While we were able to demonstrate direct p63 binding only for some of the tested corresponding mouse genomic regions possibly because of little conservation between human and mouse, the highly significant number of binding sites in the desmosomal cadherin locus indicate that this cluster might be coordinately regulated by p63.

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